Serious Muscle Injury with Statins
FDA is reminding healthcare professionals that patients who take amiodarone along with drugs that contain simvastatin have an increased risk of rhabdomyolysis, a type of muscle injury that can lead to kidney failure and death. Amiodarone is an antiarrhythmic drug and simvastatin (found in Zocor, Vytorin and Simcor) is used to lower cholesterol. This increased risk has been described in the labeling for both amiodarone and simvastatin since 2002, but FDA continues to receive reports of rhabdomyolysis in patients treated concurrently with these two drugs, especially when the simvastatin dose is greater than 20 mg per day. Prescribers should avoid doses of simvastatin greater than 20 mg per day in patients who are also taking amiodarone. When patients start taking simvastatin or their dose is increased, they should be told about the risk of rhabdomyolysis and advised to promptly report any unexplained muscle pain, tenderness or weakness.
Zocor Muscle Pain Fully Explained
November 20 2010, 5:40 pmZocor muscle pain - 4 factors that worsen zocor muscle pain. When can you experience such muscle pain?
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November 20 2010, 5:40 pmt734 - I took 40 mg a day of Zocor for 1 year then stopped in November. After about 6 months the following began. Right foot and heel pain, agitation, hazy vision, digestive problems, muscle weakness, loss of strength, slight muscle ...
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November 20 2010, 5:40 pmIn rare conditions, Zocor may lead to such conditions that may turn into collapsing skeletal muscle tissue, which may eventually lead to kidney failure. The common symptoms are unexplained muscle pain, tenderness, muscle weakness, ...
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Since I started taking Zocor, I have had severe leg cramps ...
November 20 2010, 5:40 pmAlthough there is only limited evidence for benefit, if a patient requires a statin and experiences muscle pain while on pravastatin or fluvastatin, a trial of with CoQ10 (Coenzyme Q10) supplements at 150 mg – 200 mg daily might be ...
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